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Antigenic Specificity | NFX1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against NFX1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFX1 |
Other Names | [transcriptional repressor NF-X1 isoform 1; Transcriptional repressor NF-X1; transcriptional repressor NF-X1; nuclear transcription factor, X-box binding 1; Nuclear transcription factor, X box-binding protein 1] |
Gene, Accession # | [NFX1], Gene ID: 4799, NCBI: NP_002495, UniProt: Q12986 |
Catalog # | MBS3224560 |
Price | $335 |
Order / More Info | NFX1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |