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Antigenic Specificity | Catenin-beta1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Catenin-beta1 Polyclonal Antibody detects endogenous levels of Catenin-beta1 protein. The protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), m |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Catenin-beta1 at AA range: 600-680 |
Other Names | [Rabbit Catenin-beta1; CTNNB1; OK/SW-cl.35; Catenin beta-1; Beta-catenin] |
Gene, Accession # | [CTNNB], Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222 |
Catalog # | MBS9701595 |
Price | $130, $220, $325 |
Order / More Info | Catenin-beta1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |