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Antigenic Specificity | Human Aldehyde Dehydrogenase 5 A1 |
Clone | [PAT17F5AT] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a k |
Format | Protein A purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ALDH5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase, which is a member of the aldehyde dehydrogenase family of proteins. The ALDH5A1 protein functions as a mediator to the NADP+-dependent oxidation of aldehydes into acids and has an imperative role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 is expressed in various tissues, including the liver, heart, lung, brain, kidney and placenta. Deficiency in the ALDH5A1 enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to this defect, physiologic |
Immunogen | Immunogen: Anti-human ALDH5A1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ALDH5A1 protein 48-535 amino acids purified from E Coli. |
Other Names | [ALDH5A1; Succinate-semialdehyde dehydrogenase mitochondrial; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase; ALDH5A1; SSADH; SSDH; Aldehyde Dehydrogenase 5 A1, Mouse Human], [ALDH5A1; ALDH5A1; SSDH; SSADH; SSADH] |
Gene, Accession # | [ALDH5A1], Gene ID: 7915, NCBI: EAW55454.1 |
Catalog # | MBS146656 |
Price | $140, $205, $505 |
Order / More Info | Human Aldehyde Dehydrogenase 5 A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |