Caspase-9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-9
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, other
IsotypeIgG
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Western blot analysis of extracts of C6 cells (rat), untreated or treated with staurosporine or cytochrome c as indicated, using caspase-9 antibody. Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1, 2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to ini
ImmunogenImmunogen: Recombinant protein of human Caspase-9
Other Names[caspase-9; Caspase-9; caspase-9; caspase 9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3]
Gene, Accession #Gene ID: 842, NCBI: BAA87905.1
Catalog #MBS4150059
Price$385
Order / More InfoCaspase-9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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