ZAP70 (Chronic Lymphocytic Leukemia Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-ZAP70 (Chronic Lymphocytic Leukemia Marker) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | ZAP70 (Chronic Lymphocytic Leukemia Marker) |
| Clone | [ZAP70/528] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. |
| Immunogen | Immunogen: Recombinant full-length human ZAP70 protein |
| Other Names | [Selective T cell defect; SRK; STD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70;TZK; Zeta chain associated protein kinase 70kDa], [ZAP70; ZAP70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70; SRK] |
| Gene, Accession # | [ZAP70], Gene ID: 7535, NCBI: NP_001070.2, UniProt: P43403 |
| Catalog # | MBS438538 |
| Price | $190, $340, $340 |
| Order / More Info | ZAP70 (Chronic Lymphocytic Leukemia Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Iwashima M, Irving BA, van Oers NSC, Chan AC, Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 1994;263:1136-9 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies