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Antigenic Specificity | EIF2AK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.3 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total EIF2AK3 protein. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human eukaryotic translation initiation factor 2-alpha kinase 3 |
Other Names | [PEK; WRS; PERK] |
Gene, Accession # | [EIF2AK3], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5 |
Catalog # | MBS9403654 |
Price | $255 |
Order / More Info | EIF2AK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |