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Antigenic Specificity | ULK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ULK2 antibody detects endogenous levels of total ULK2. Function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in |
Immunogen | Immunogen: A synthesized peptide derived from human ULK2 Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (91%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (92%) |
Other Names | [ATG1B; KIAA0623; Serine/threonine protein kinase ULK2; Serine/threonine-protein kinase ULK2; ULK2; ULK2_HUMAN; Unc 51 (C. elegans) like kinase 2; Unc 51 like autophagy activating kinase 2; Unc 51 like kinase 2; Unc-51-like kinase 2; Unc51.2] |
Gene, Accession # | [ULK2], Gene ID: 9706, NCBI: NP_001136082.1, UniProt: Q8IYT8 |
Catalog # | MBS9610206 |
Price | $240, $280 |
Order / More Info | ULK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |