GRK6 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GRK6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total GRK6 protein. Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).Stoffel R.H., J. Biol. Chem. 269:2 |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human GRK6. |
| Other Names | [EC 2.7.11.16; G-protein-coupled receptor kinase 6; GPRK6; kinase GRK6] |
| Gene, Accession # | [GRK6], Gene ID: 2870, NCBI: NP_001004105.1, UniProt: P43250 |
| Catalog # | MBS9411264 |
| Price | $200, $255 |
| Order / More Info | GRK6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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