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Antigenic Specificity | SC65 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SC65 antibody detects endogenous levels of total SC65. Function: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.Subunit Structure: Interacts with PLOD1, P3H3 and PPIB. Identified in a complex with PLOD1 and P3H3.Similarity: Belongs to the leprecan family. |
Immunogen | Immunogen: A synthesized peptide derived from human SC65 Subcellular Location: Endoplasmic Reticulum Tissue Specificity: Detected in fibroblasts (at protein level) (PubMed:23959653). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778). Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (91%) |
Other Names | [Leprecan-like protein 4; Leprel4; NOL55; Nucleolar autoantigen 55kDa; Nucleolar autoantigen No55; OTTHUMP00000164758; SC 65; SC65_HUMAN; Synaptonemal complex protein SC65] |
Gene, Accession # | [SC65], Gene ID: 10609, NCBI: NP_006446.1, UniProt: Q92791 |
Catalog # | MBS9610032 |
Price | $240, $280 |
Order / More Info | SC65 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |