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Antigenic Specificity | CD14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD14 is a glycophosphatidylinositolanchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It acts as a coreceptor for the detection of bacterial lipopolysaccharide (LPS) (1). CD14 cooperates with MD2 and TLR4 to mediate the innate immune response to bacterial LPS. It acts via MyD88, TIRAP and TRAF6, leading to NFkappaB activation, cytokine secretion and the inflammatory response (2). CD14 is expressed strongly on peripheral blood monocytes and macrophages, and weakly on the surface of granulocytes (1). |
Immunogen | Immunogen: A synthetic peptide of human CD14 |
Other Names | [CD14; CD14; Monocyte differentiation antigen CD14;], [CD14; CD14] |
Gene, Accession # | Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571 |
Catalog # | MBS127729 |
Price | $275, $430, $655 |
Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Shimizu, T., et al. Clinical and Diagnostic Laboratory Immunology 969976, 2004 2. The UniProt Consortium, The Universal Protein Resource (UniProt) Nucleic Acids Res. 36:D190D195, 2008 |