CD14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD14
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionCD14 is a glycophosphatidylinositolanchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It acts as a coreceptor for the detection of bacterial lipopolysaccharide (LPS) (1). CD14 cooperates with MD2 and TLR4 to mediate the innate immune response to bacterial LPS. It acts via MyD88, TIRAP and TRAF6, leading to NFkappaB activation, cytokine secretion and the inflammatory response (2). CD14 is expressed strongly on peripheral blood monocytes and macrophages, and weakly on the surface of granulocytes (1).
ImmunogenImmunogen: A synthetic peptide of human CD14
Other Names[CD14; CD14; Monocyte differentiation antigen CD14;], [CD14; CD14]
Gene, Accession #Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571
Catalog #MBS127729
Price$275, $430, $655
Order / More InfoCD14 Antibody from MYBIOSOURCE INC.
Product Specific References1. Shimizu, T., et al. Clinical and Diagnostic Laboratory Immunology 969976, 2004 2. The UniProt Consortium, The Universal Protein Resource (UniProt) Nucleic Acids Res. 36:D190D195, 2008
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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