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Antigenic Specificity | SHP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SHP2 Antibody: Src homology-2 domain containing protein (SHP2) is a member of the protein tyrosine phosphatase (PTP) family, a protein family that contains signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. SHP2 contains two tandem Src homology-2 (SH2) domains, which function as phosphotyrosine binding domains either directly or through scaffolding intermediates such as the insulin-receptor substrate 1 (IRS-1). These SH2 domains mediate the interaction of SHP2 with its substrates, allowing SHP2 to dephosphorylate proteins that inhibit signaling kinases such as ERK1 and AKT. SHP2 is widely expressed in most tissues and plays a regulatory role |
Immunogen | Immunogen: SHP2 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human SHP2. Buffer: SHP2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SHP2; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; protein tyrosine phosphatase, non-receptor type 11], [PTPN11; PTPN11; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2] |
Gene, Accession # | [PTPN11], Gene ID: 5781, NCBI: NP_002825, UniProt: Q06124 |
Catalog # | MBS150386 |
Price | $375 |
Order / More Info | SHP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |