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Antigenic Specificity | NMDAR1 (Phospho-Ser896) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of NMDAR1 only when phosphorylated at serine896. NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation ( |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 896 (R-R-S(p)-S-K) derived from Human NMDAR1. |
Other Names | [GLURZ1; GRIN1; NMD-R1; NMDZ1; NMZ1] |
Gene, Accession # | [NMDAR1], Gene ID: 2902, NCBI: NP_000823.4, UniProt: Q05586 |
Catalog # | MBS9401431 |
Price | $200, $255 |
Order / More Info | NMDAR1 (Phospho-Ser896) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |