Edit |   |
---|---|
Antigenic Specificity | Phospho-Cofilin (Tyr140) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Cofilin (Tyr140) Antibody detects endogenous levels of Cofilin only when phosphorylated at Tyr140. Description: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).Post Transl |
Immunogen | Immunogen: A synthesized peptide derived from human Cofilin around the phosphorylation site of Tyr140. Tissue Specificity: Widely distributed in various tissues. |
Other Names | [18 kDa phosphoprotein; CFL 1; CFL1; COF1_HUMAN; Cofilin 1; Cofilin 1 non muscle; Cofilin; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18] |
Gene, Accession # | [CFL], Gene ID: 1072, NCBI: NP_005498.1, UniProt: P23528 |
Catalog # | MBS9610628 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Cofilin (Tyr140) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |