BCL2L2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBCL2L2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman. predicted: mouse, rat.
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration100ug/100ul
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
ImmunogenImmunogen: Rabbit polyclonal BCL2L2 (1) antibody was raised against full length recombinate human BCL2L2 protein (NM 004050.4).
Other Names[bcl-2-like protein 2; Bcl-2-like protein 2; bcl-2-like protein 2; apoptosis regulator BCL-W; protein phosphatase 1, regulatory subunit 51; BCL2-like 2; Apoptosis regulator Bcl-W], [BCL2L2; BCL2L2; BCLW; BCL-W; PPP1R51; BCL2-L-2]
Gene, Accession #[BCL2L2], Gene ID: 599, NCBI: NP_001186768.1
Catalog #MBS416553
Price$230
Order / More InfoBCL2L2 Antibody from MYBIOSOURCE INC.
Product Specific References(1) Ku,B., Liang,C., Jung,J.U. et al. Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. Cell Res. 21 (4), 627-641 (2011).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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