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Antigenic Specificity | BCL2L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010] |
Immunogen | Immunogen: Rabbit polyclonal BCL2L2 (1) antibody was raised against full length recombinate human BCL2L2 protein (NM 004050.4). |
Other Names | [bcl-2-like protein 2; Bcl-2-like protein 2; bcl-2-like protein 2; apoptosis regulator BCL-W; protein phosphatase 1, regulatory subunit 51; BCL2-like 2; Apoptosis regulator Bcl-W], [BCL2L2; BCL2L2; BCLW; BCL-W; PPP1R51; BCL2-L-2] |
Gene, Accession # | [BCL2L2], Gene ID: 599, NCBI: NP_001186768.1 |
Catalog # | MBS416553 |
Price | $230 |
Order / More Info | BCL2L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Ku,B., Liang,C., Jung,J.U. et al. Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. Cell Res. 21 (4), 627-641 (2011). |