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Antigenic Specificity | CD3 (T3)-Hu |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human CD3 protein. The other species was not tested. CD3 is a glycoprotein consisting of up to five polypeptide chains (gp20, gp26, p16, p20, p28). CD3 is required for proper assembly, trafficking and surface expression of TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. CD3 is involved in T cell activation, proliferation and apoptosis pathway. This protein is present on virtually all peripheral blood T cells and thymocytes. This anti-CD3 antibody is commonly used as a phenotypic marker for human T cells. |
Immunogen | n/a |
Other Names | [CD3], [CD247; cd3g; T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA] |
Gene, Accession # | [CD3], Gene ID: 919, NCBI: CAA72995.1, UniProt: P79951 |
Catalog # | MBS460440 |
Price | $285 |
Order / More Info | CD3 (T3)-Hu Antibody from MYBIOSOURCE INC. |
Product Specific References | Kearse KP. Calnexin associates with monomeric and oligomeric (disulfidelinked) CD3delta proteins in murine T lymphocytes. J Biol Chem. 1998 Jun 5I3/4273 (23):141527. |