TrkA . Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TrkA . |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.60 ug/ul IgY in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor tyrosine kinases (RTK)s are high-affinity cell surface receptors for many polypeptide rowthfactors, cytokines, and hormones (1). TrkA is part of a sub-family of protein kinases which includes TrkBand TrkC (2). Tyrosine Receptor Kinase A (TrkA) is a receptor tyrosine kinase involved in thedevelopment and the maturation of the central and peripheral nervous systems through regulation ofproliferation, differentiation and survival of sympathetic nervous neurons. TrkA is a high affinity receptorfor NGF, its primary ligand, but also binds and can be activated via NTF3/neutrophin-3. NGF is importantin both local and nuclear actions, regulating growth ones, motility, and expression of genes encodingbiosynthesis of enzymes for neurot |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 360-410 on human TrkA protein. Immunoglobulin: IgY Expression: Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors. |
| Other Names | [CIPA; gp140trk; High affinity nerve growth factor receptor; MTC; Neurotrophic tyrosine kinase receptor type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth; TRK; Trk-A; TRK1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor A] |
| Gene, Accession # | [TrkA], Gene ID: 4914, NCBI: BAA34355.1, UniProt: P04629 |
| Catalog # | MBS5400171 |
| Price | $390 |
| Order / More Info | TrkA . Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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