AP-2alpha Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AP-2alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human AP-2alpha. The sequence-specific transcription factor activator protein 2alpha (AP-2alpha) is required for normal growth and morphogenesis during mammalian development (1,2). Decreased or loss of AP-2alpha expression has been observed in many different types of human cancers including breast cancer (3,4), ovarian cancer (5), melanoma (6) and prostate cancer (7). These findings suggest that AP-2alpha expression plays a crucial role in tumorigenicity. Studies have also shown that p53 overexpression in human breast carcinoma cells induces the level of AP-2alpha expression. Furthermore, p53 binds to the cis-element in the AP-2alpha promoter, suggesting that AP-2alpha is a target of p53. AP-2alpha may mediate the effec |
| Immunogen | Immunogen: A fusion protein of human AP-2alpha |
| Other Names | [TFAP2A; AP-2alpha; AP-2a; TFAP2A; AP-2; AP-2alpha; AP2TF; BOFS; FLJ51761; TFAP2; AP2], [TFAP2A; TFAP2A; AP-2; BOFS; AP2TF; TFAP2; AP-2alpha; AP2TF; TFAP2; AP2-alpha; AP-2] |
| Gene, Accession # | Gene ID: 7020, NCBI: NP_001027451.1, UniProt: P05549 |
| Catalog # | MBS125382 |
| Price | $200, $275, $430 |
| Order / More Info | AP-2alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Mitchell, P.J. et al. (1987) Cell 50, 847-61. 2. Williams, T. and Tjian, R. (1991) Genes Dev 5, 670-82. 3. Douglas, D.B. et al. (2004) Cancer Res 64, 1611-20. 4. Gee, J.M. et al. (1999) J Pathol 189, 514-20. 5. Anttila, M.A. et al. (2000) Br J Cancer 82, 1974-83. 6. Jean, D. et al. (1998) J Biol Chem 273, 16501-8. 7. Ruiz, M. et al. (2004) Cancer Res 64, 631-8. 8. Li, H. et al. (2006) Oncogene 25, 5405-15. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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