GAD2/GAD65 (GABAergic Neuronal Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GAD2/GAD65 (GABAergic Neuronal Marker) |
| Clone | [GAD2/1960] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2b, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified i |
| Immunogen | Immunogen: Recombinant human GAD2 (GAD65) protein fragment (around aa 6-99) Cellular Localization: Cytoplasmic |
| Other Names | [DCE2; GAD2; Glutamic Acid Decarboxylase 2 (Pancreas); Glutamic Acid Decarboxylase 2 (Pancreatic Islets and Brain 65kDa); Glutamic Acid Decarboxylase 65 (GAD65)] |
| Gene, Accession # | [GAD2], Gene ID: 2572, NCBI: NP_000809.1, UniProt: Q05329 |
| Catalog # | MBS4380443 |
| Price | $190, $340, $340 |
| Order / More Info | GAD2/GAD65 (GABAergic Neuronal Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kaufman DL., et al. J Clin Invest. 1992 Jan; 89(1):283-92. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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