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Antigenic Specificity | ERO1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ERO1L Antibody detects endogenous levels of ERO1L. Description: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-depende |
Immunogen | Immunogen: A synthesized peptide derived from human ERO1L. Tissue Specificity: Widely expressed at low level. Expressed at high level in upper digestive tract. Highly expressed in esophagus. Weakly expressed in stomach and duodenum. |
Other Names | [Endoplasmic oxidoreductin 1 like protein; Endoplasmic oxidoreductin-1-like protein; Endoplasmic reticulum oxidoreductase 1 alpha; Endoplasmic reticulum oxidoreductin 1-like; ERO1 alpha; ERO1 L; ERO1 Lalpha; ERO1 like protein alpha; ERO1-alpha; ERO1-L; ERO1-L-alpha; ERO1-like (S. cerevisiae); ERO1-like alpha; ERO1-like protein alpha; ERO1-like, S. cerevisiae, homolog of, alpha; ERO1A; ERO1A_HUMAN; ERO1L; ERO1LA; Oxidoreductin 1 Lalpha; Oxidoreductin-1-L-alpha; PRO865; UNQ434] |
Gene, Accession # | [ERO1L], Gene ID: 30001, NCBI: NP_055399, UniProt: Q96HE7 |
Catalog # | MBS9611735 |
Price | $240, $280 |
Order / More Info | ERO1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |