Edit |   |
---|---|
Antigenic Specificity | LRSAM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human LRSAM1 (NP 612370.3). |
Other Names | [TAL; CMT2P; RIFLE] |
Gene, Accession # | [LRSAM1], Gene ID: 90678, NCBI: NP_001005373.1, UniProt: Q6UWE0 |
Catalog # | MBS8547677 |
Price | $280 |
Order / More Info | LRSAM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |