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Antigenic Specificity | RAG2 |
Clone | [4D5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin co |
Immunogen | Immunogen: Purified recombinant fragment of human RAG2(350-527aa) expressed in E. Coli. |
Other Names | [RAG-2; RAG2] |
Gene, Accession # | [RAG2], Gene ID: 5897, NCBI: NP_000527.2, UniProt: P55895 |
Catalog # | MBS8538614 |
Price | $280 |
Order / More Info | RAG2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |