Rec.Pr.Thyrosin Phosphate (RPTP) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRec.Pr.Thyrosin Phosphate (RPTP)
Clone[3D7]
Host SpeciesMouse (Balb/c)
Reactive Specieshuman, rat, porcine
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionSpecificity: Monoclonal antibodies 3G4 and 3D7 have been directed anti the extracellular domain of RPTPu. Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substRates. RPTPu is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPu consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPu is Catalytically active, whereas its second (C-terminal) domain is inactive. RPTPu is involved
ImmunogenSource Note: 3D7 is a Mouse monoclonal IgG2a antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPu molecule (aa 1-742), fused COOH terminally to GST.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS570235
Price$770
Order / More InfoRec.Pr.Thyrosin Phosphate (RPTP) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGerben C. M. Zondag, Albert B. Reynolds , and Wouter H. Moolenaar. THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 275, No. 15, Issue of April 14, pp. 11264-11269, 2000.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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