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Antigenic Specificity | HAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HAT protein. Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human HAT. |
Other Names | [Histone acetyltransferase 1; Histone acetyltransferase type B catalytic subunit; EC 2.3.1.48; HAT1] |
Gene, Accession # | [HAT], Gene ID: 8520, NCBI: NP_003633.1, UniProt: O14929 |
Catalog # | MBS9407589 |
Price | $200, $255 |
Order / More Info | HAT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |