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Antigenic Specificity | ATP7A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATP7A Polyclonal Antibody detects endogenous levels of ATP7A protein. ATP7A (ATPase copper transporting alpha) encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in ATP7A are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human ATP7A |
Other Names | [Rabbit ATP7A; ATP7A; MC1; MNK; Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein] |
Gene, Accession # | [ATP7A], Gene ID: 538, NCBI: NP_000043.3, UniProt: Q04656 |
Catalog # | MBS9706257 |
Price | $130, $220, $325 |
Order / More Info | ATP7A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |