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Antigenic Specificity | ATG4A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
Immunogen | Immunogen: Recombinant human Cysteine protease ATG4A protein(1-214AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-131433 / sc-131435 / sc-131432 |
Other Names | [AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A; ATG4A; APG4A; AUTL2], [ATG4A; ATG4A; APG4A; AUTL2; APG4A; AUTL2; hAPG4A] |
Gene, Accession # | [ATG4A], Gene ID: 115201, NCBI: NP_443168.2, UniProt: Q8WYN0 |
Catalog # | MBS968765 |
Price | $160, $235 |
Order / More Info | ATG4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |