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Antigenic Specificity | CD161 |
Clone | [ABM2D74] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin super family. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD). |
Immunogen | Immunogen: A full length of human CD161 protein were used as the immunogen for this antibody. |
Other Names | [killer cell lectin-like receptor subfamily B member 1; Killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B, member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD_antigen: CD161], [KLRB1; KLRB1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; CLEC5B; NKRP1A; NKR-P1A] |
Gene, Accession # | [CD161], Gene ID: 3820, NCBI: NP_002249.1, UniProt: Q12918 |
Catalog # | MBS668177 |
Price | $175 |
Order / More Info | CD161 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |