Stargazin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Stargazin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat (predicted: mouse, assumed based on 100% homology with sequence used as antigen) |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for the ~36k stargazin protein. Description: Affinity purified rabbit polyclonal antibody. Biological Significance: Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). |
| Immunogen | Antigen: Peptide corresponding to amino acid residues from the C-terminal region of rat stargazin, conjugated to keyhole limpet hemocyanin (KLH). |
| Other Names | [voltage-dependent calcium channel gamma-2 subunit; Voltage-dependent calcium channel gamma-2 subunit; voltage-dependent calcium channel gamma-2 subunit; TARP gamma 2; TARP gamma-2; transmembrane AMPAR regulatory protein gamma-2; neuronal voltage-gated calcium channel gamma-2 subunit; calcium channel, voltage-dependent, gamma subunit 2; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; Transmembrane AMPAR regulatory protein gamma-2], [Cacng2; Cacng2; stg; wag; waggler; AW060990; stargazer; stargazin; B230105C07Rik; B930041E13Rik; Stg; TARP gamma-2] |
| Gene, Accession # | [CACNG2], Gene ID: 12300, NCBI: NP_031609.1, UniProt: O88602 |
| Catalog # | MBS502114 |
| Price | $360 |
| Order / More Info | Stargazin Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS,(2005) Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature 435: 1052-1058.• Priel A, Kolleker A, Ayalon G, Gillor M, Osten P, Stern-Bach Y. (2005) Stargazin reduces desensitization and slows deactivation of the AMPA-type glutamate receptors. J. Neurosci. 25, 2682-2686.• Choi, J, Ko J, Park E, Lee JR, Yoon J, Lim S, Kim E, Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95.J Biol Chem. 2002 Apr 5;277(14):12359-63. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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