TTF-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTTF-1
Clone[8G7G3/1]
Host SpeciesMouse
Reactive Specieshuman, dog
IsotypeIgG1
Formatunconjugated
Size5 Control Slides, 3 ml (Prediluted), 7 mL (Prediluted)
Concentrationn/a
Applicationsn/a
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DescriptionThyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific to the thyroid, lung and diencephalon. It is also known as thyroid-specific enhancer binding protein and NKX-2. It is used as a marker to determine if a tumor oringinates in the lung or thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular cells are positive. TTF-1 is useful in differentiating primary Adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma. It can also be used to differentiate Small- Cell Lung Carcinoma from lymphoid infiltrates. For lung cancers, Adenocarcinomas are usually positive, while Squamous Cell C
Immunogenn/a
Other Names[homeobox protein Nkx-2.1 isoform 1; Homeobox protein Nkx-2.1; homeobox protein Nkx-2.1; NK-2 homolog A; OTTHUMP00000178847; OTTHUMP00000225297; thyroid nuclear factor 1; thyroid transcription factor 1; homeobox protein NK-2 homolog A; NK2 homeobox 1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1], [NKX2-1; NKX2-1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; TITF1; TTF-1; NKX2.1; NKX2A; TITF1; TTF1]
Gene, Accession #[TTF-1], Gene ID: 7080, NCBI: NP_001073136.1, UniProt: Q7KZF6
Catalog #MBS370112
Price$130, $170, $190
Order / More InfoTTF-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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