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Antigenic Specificity | TTF-1 |
Clone | [8G7G3/1] |
Host Species | Mouse |
Reactive Species | human, dog |
Isotype | IgG1 |
Format | unconjugated |
Size | 5 Control Slides, 3 ml (Prediluted), 7 mL (Prediluted) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific to the thyroid, lung and diencephalon. It is also known as thyroid-specific enhancer binding protein and NKX-2. It is used as a marker to determine if a tumor oringinates in the lung or thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular cells are positive. TTF-1 is useful in differentiating primary Adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma. It can also be used to differentiate Small- Cell Lung Carcinoma from lymphoid infiltrates. For lung cancers, Adenocarcinomas are usually positive, while Squamous Cell C |
Immunogen | n/a |
Other Names | [homeobox protein Nkx-2.1 isoform 1; Homeobox protein Nkx-2.1; homeobox protein Nkx-2.1; NK-2 homolog A; OTTHUMP00000178847; OTTHUMP00000225297; thyroid nuclear factor 1; thyroid transcription factor 1; homeobox protein NK-2 homolog A; NK2 homeobox 1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1], [NKX2-1; NKX2-1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; TITF1; TTF-1; NKX2.1; NKX2A; TITF1; TTF1] |
Gene, Accession # | [TTF-1], Gene ID: 7080, NCBI: NP_001073136.1, UniProt: Q7KZF6 |
Catalog # | MBS370112 |
Price | $130, $170, $190 |
Order / More Info | TTF-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |