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Antigenic Specificity | RNUXA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RNUXA antibody detects endogenous levels of total RNUXA. Function: A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-an |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus > Nucleoplasm. Nucleus > Cajal Body. Cytoplasm. Located in the nucleoplasm and cajal bodies. Shuttles between the nucleus and the cytoplasm. Shuttles between the nucleoplasm and cajal bodies. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (92%), Bovine (92%), Horse (100%), Sheep (92%), Rabbit (92%), Dog (100%), Chicken (92%), Xenopus (82%) |
Other Names | [FLJ13193; PHAX; PHAX_HUMAN; Phosphorylated adapter RNA export protein; Phosphorylated adaptor for RNA export; RNA U small nuclear RNA export adapter protein; RNA U, small nuclear RNA export adapter (phosphorylation regulated); RNUXA] |
Gene, Accession # | [RNUXA], Gene ID: 51808, NCBI: NP_115553.2, UniProt: Q9H814 |
Catalog # | MBS9605900 |
Price | $240, $280 |
Order / More Info | RNUXA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |