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Antigenic Specificity | ITGB2 |
Clone | [534CT6.2.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged ITGB2 protein(Fragment) was used to produced this monoclonal antibody. The product of this gene belongs to the integrin betachain family of proteins. Integrins are integral cell-surfaceproteins composed of an alpha chain and a beta chain. This geneencodes the integrin beta chain beta 2. A given chain may combinewith multiple partners resulting in different integrins. Forexample, beta 2 combines with the alpha L chain to form theintegrin LFA-1, and combines with the alpha M chain to form theintegrin Mac-1. Integrins are known to participate in cell adhesionas well as cell-surface mediated signalling. Defects in this geneare the cause of leukocyte adhesion deficiency type I |
Immunogen | n/a |
Other Names | [Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; CD18; MFI7] |
Gene, Accession # | [ITGB2], Gene ID: 3689, NCBI: NP_000202.2, UniProt: P05107 |
Catalog # | MBS9200311 |
Price | $370 |
Order / More Info | ITGB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gjelstrup, L.C., et al. J. Immunol. 185(7):4154-4168(2010) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14727-14732(2010) Pliyev, B.K., et al. Biochem. Biophys. Res. Commun. 397(2):277-282(2010) |