Human TrkA/NTRK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman TrkA/NTRK1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionTRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed. Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors. The presence of NTRK1 leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
ImmunogenImmunogen: Recombinant Human TrkA/NTRK1 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
Other Names[TRKA; High affinity nerve growth factor receptor; high affinity nerve growth factor receptor; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; Trk-A; gp140trk; p140-TrkA]
Gene, Accession #[TrkA/NTRK1 ], Gene ID: 4914
Catalog #MBS2544163
Price$215, $330, $500
Order / More InfoHuman TrkA/NTRK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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