Edit |   |
---|---|
Antigenic Specificity | CaVbeta2 |
Clone | [S8b-1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | ATTO 594 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~78 kDa. No cross reactivity against Cavbeta1, Cavbeta3, Cavbeta4 Scientific Background: Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (3). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (4, 5). They also determine the biophysical properties of the calcium channel (5). |
Immunogen | n/a |
Other Names | [Cacnlb2; cacnb2; Voltage-dependent L-type calcium channel subunit beta-2; CAB2], [Cacnb2; Cacnb2; Cacnlb2; Cacnlb2; CAB2] |
Gene, Accession # | Gene ID: 116600, NCBI: NP_446303, UniProt: Q8VGC3 |
Catalog # | MBS800089 |
Price | $440 |
Order / More Info | CaVbeta2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Dolphin A.C. (2003) J Bioenerg. Biomembr. 35: 599-620. 4. Bichet D., et al. (2000) Neuron. 25: 177-190. 5. Xie M., et al. (2007) J Cell Biol. 178(3): 489-502. |