JAG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJAG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: JAG1 antibody is human, mouse and rat reactive. At least two isoforms of JAG1 are known to exist; this antibody will detect both isoforms. The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate decisions (1). Ligands for Notch include JAG1, JAG2 and Delta. JAG1 is one of the DSL (Delta, Serrate, Lag2) transmembrane proteins that can activate Notch. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis (1,2). JAG1 is widely expressed in adult and fetal tissues and the mutation of the JAG1 gene is associated with Familial Tetrology of Fallot (3). JAG1 expression is associated with prostate cancer metastasis and is up-regulated
ImmunogenImmunogen: JAG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAG1. Buffer: JAG1 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Jagged 1; AGS; AHD; AWS; CD339; HJ1; JAGL1; jagged 1], [JAG1; JAG1; AGS; AHD; AWS; HJ1; CD339; JAGL1; JAGL1; Jagged1; hJ1]
Gene, Accession #[JAG1], Gene ID: 182, NCBI: NP_000205, UniProt: P78504
Catalog #MBS153705
Price$375
Order / More InfoJAG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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