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Antigenic Specificity | KDM4B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 3.2mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | JMJD2B (JmjC domain-containing histone demethylation protein 3A) is a 1, 064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker a |
Immunogen | Immunogen: Synthetic peptide of human KDM4B |
Other Names | [JMJD2B; TDRD14B] |
Gene, Accession # | [KDM4B], NCBI: AIC59790.1 |
Catalog # | MBS2528729 |
Price | $110, $150, $225 |
Order / More Info | KDM4B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |