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Antigenic Specificity | alpha-Internexin [1D2] |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.5 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-Internexin is a ~66 kDa Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnosti |
Immunogen | Immunogen: Purified recombinant rat alpha-internexin expressed in and purified from E Coli. Specifically recognizes the C-terminal non-helical extension of a-internexin. |
Other Names | [alpha-internexin; Alpha-internexin; alpha-internexin; internexin neuronal intermediate filament protein alpha; 66 kDa neurofilament protein; NF-66; Neurofilament-66; Neurofilament 5], [INA; INA; NEF5; NF-66; TXBP-1; NEF5; Alpha-Inx; NF-66; Neurofilament-66] |
Gene, Accession # | Gene ID: 9118, NCBI: NP_116116.1 |
Catalog # | MBS555019 |
Price | $380 |
Order / More Info | alpha-Internexin [1D2] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |