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Antigenic Specificity | TXNRD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the pyridine nucleotidedisulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conservedstem-loop structure, the Sec insertion sequence (SECIS) elem |
Immunogen | Immunogen: Recombinant protein of human TXNRD2 Calculated MW: 30kDa/46kDa/53kDa/56kDa Observed MW: 56kDa Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [SELZ;TR;TR-BETA;TR3;TRXR2] |
Gene, Accession # | [TXNRD2], Gene ID: 10587, NCBI: NP_001269441.1 |
Catalog # | MBS2523012 |
Price | $150, $225, $360 |
Order / More Info | TXNRD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |