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Antigenic Specificity | GNB2L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression (PubMed:23636399). Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (PubMed:28132843). Binds to and stabilizes activated protein kinase C (PKC), increasing PKC-mediated phosphorylation. May recruit activated PKC to the ribosome, leading to phosphorylation of EIF6. Inhibits the activity of SRC kinases including SRC, |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human GNB2L1 (NP 006089.1). |
Other Names | [H12.3; HLC-7; PIG21; GNB2L1; Gnb2-rs1; RACK1] |
Gene, Accession # | [GNB2L1], Gene ID: 10399, NCBI: NP_006089.1, UniProt: P63244 |
Catalog # | MBS8548990 |
Price | $280 |
Order / More Info | GNB2L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |