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Antigenic Specificity | TRIM24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of TRIM24 are known to exist. TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC). |
Immunogen | Immunogen: TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. Buffer: TRIM24 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRIM24; PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; Transcription intermediary factor 1-alpha; E3 ubiquitin-protein ligase TRIM24; TIF1-alpha; tripartite motif containing 24], [TRIM24; TRIM24; PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; RNF82; TIF1; TIF1A; TIF1-alpha] |
Gene, Accession # | [TRIM24], Gene ID: 8805, NCBI: NP_056989, UniProt: O15164 |
Catalog # | MBS153590 |
Price | $375 |
Order / More Info | TRIM24 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |