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Antigenic Specificity | Chapsyn-110, 1-852 |
Clone | [S18-30] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot; Immunocytochemistry; Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Chapsyn-110. This antibody recognizes human (weak), mouse, and rat Chapsyn-110. It does not react with PSD-95, SAP97, or SAP102. Chapsyn-110 is a member of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor and Shaker K+ channel subunits and is 70-80% identical to PSD-95/SAP90 and SAP97. It mediates clustering of both NMDA receptors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multlimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. |
Immunogen | Antigen: Fusion protein corresponding to aa 1-852 of rat Chapsyn-110 (accession no. Q63622). This sequence is 94% homologous with human and 99% homologous with mouse Chapsyn-110. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS190527 |
Price | $410 |
Order / More Info | Chapsyn-110, 1-852 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |