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Antigenic Specificity | Human CD62P |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes P-selectin of a variety of mammals. The antibody blocks leukocyte adhesion to P-selectin and to platelets. CD62P, P-selectin, is a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. |
Immunogen | Immunogen: P-selectin transfected mouse L1-2 pre-B cells |
Other Names | n/a |
Gene, Accession # | [CD62P] |
Catalog # | MBS418466 |
Price | $370 |
Order / More Info | Human CD62P Antibody from MYBIOSOURCE INC. |
Product Specific References | Jutila MA, et al. Cell surface P- and E-selectin support shear-dependent rolling of bovine gamma/delta T cells. J. Immunol. 153: 3917-3928, 1994. |