SOX2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySOX2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Western blot analysis of brain cell lysate using SOX2 antibody. Embryonic stem cells are derived from the inner cell mass of the blastocyst and are unique in their pluripotent capacity and potential for self-renewal. Sox2 is one of a set of transcription factors that are crucial for the maintenance of pluripotency (1). Sox2, Oct-4, and Nanog cooperate in this network (1-3), and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency (4,5). Chromatin immunoprecipitation experiments have shown that Sox2 and Oct-4 bind to thousands of gene regulatory sites, highlighting the importance of these transcription factors in early embryonic development (6, 7). It has recently been shown that Sox2 is amplified in lung and
ImmunogenImmunogen: Recombinant protein of human SOX2
Other Names[SOX2, partial; SOX2; transcription factor SOX-2; SOX2], [SOX2; SOX2]
Gene, Accession #[SOX2], Gene ID: 100075503, NCBI: AAM51630.1
Catalog #MBS419451
Price$385
Order / More InfoSOX2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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