DNA Methyltransferase 3a Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DNA Methyltransferase 3a |
| Clone | [64B814.1] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1kappa |
| Format | Protein G purified |
| Size | 0.05 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect DNMT3a in Human and Mouse samples. Background: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, three families of mammalian DNA methyltransferase genes have been identified which include DNMT1, DNMT2, and DNMT3. DNMT1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. DNMT2 is expressed at low levels in adult tissues and its inactivation does not affect DNA m |
| Immunogen | Immunogen: Recombinant mouse His-tagged DNMT3a expressed in bacteria. Positive Control: Western blot: Transfected 293 cell lysate, untransfected 293 cell lysate |
| Other Names | [DNMT3; DNMT3A], [Dnmt3a; Dnmt3a; MmuIIIA; Dnmt3a; DNA MTase MmuIIIA; M.MmuIIIA] |
| Gene, Accession # | Gene ID: 13435, NCBI: NP_001258682.1, UniProt: O88508 |
| Catalog # | MBS840102 |
| Price | $270 |
| Order / More Info | DNA Methyltransferase 3a Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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