Human g-Catenin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman g-Catenin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAlso known as plakoglobin, gamma-catenin is a member of the Armadillo family of signaling molecules, which includes beta-catenin and the Drosophila protein armadillo (1). This family of proteins is involved in Wnt signaling, which is important in embryonic development and in tumorigenesis (2-3). Although the two vertebrate proteins beta- and gamma-catenin display sequence homology, gamma-catenin likely plays a role distinct from that of beta-catenin (1, 4-6). gamma-catenin localizes to desmosomes and adherens junctions, both sites of intercellular adhesion, and interacts with the cytoplasmic domains of classical and desmosomal cadherins. Interaction of gamma- or beta-catenin with alpha-catenin, desmoplakin and other junction proteins provid
ImmunogenImmunogen: A fusion protein of human g-Catenin
Other Names[y-Catenin; y-Catenin Rabbit pab; gamma-Catenin Rabbit pab], [JUP; ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB]
Gene, Accession #Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923
Catalog #MBS125248
Price$275, $430
Order / More InfoHuman g-Catenin Antibody from MYBIOSOURCE INC.
Product Specific References1. Zhurinsky, J. et al. (2000) J. Cell Sci. 113 (Pt 18), 3127-3139.2. Wodarz, A. and Nusse, R. (1998) Annu. Rev. Cell Dev. Biol. 14, 59-88.3. Polakis, P. (1999) Curr. Opin. Genet. Dev. 9, 15-21.4. Zhurinsky, J. et al. (2000) Mol. Cell Biol. 20, 4238-4252.5. Charpentier, E. et al. (2000) J. Cell Biol. 149, 503-520.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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