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Antigenic Specificity | Bim EL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist; this antibody only detects the Bim EL isoform. Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2). |
Immunogen | Immunogen: Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim. Buffer: Bim EL Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bim EL; BAM; BIM; BOD; Bcl-2-like protein 11; Bcl2-interacting mediator of cell death; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator)], [BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11] |
Gene, Accession # | [BCL2L11], Gene ID: 10018, NCBI: NP_619527, UniProt: O43521 |
Catalog # | MBS153493 |
Price | $375 |
Order / More Info | Bim EL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |