KCC2/SLC12A5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKCC2/SLC12A5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for KCC2/SLC12A5 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Potassium-chloride transporter member 5 is also known by the names: KCC2 (potassium chloride cotransporter 2) for its ionic substrates, and SLC12A5 for its genetic origin from the SLC12A5 gene in humans. It is mapped to 20q13.12. K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients
ImmunogenImmunogen: E Coli-derived human KCC2/SLC12A5 recombinant protein (Position: A228-N833). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P).
Other Names[Solute carrier family 12 member 5; Solute carrier family 12 member 5; Electroneutral potassium-chloride cotransporter 2; K-Cl cotransporter 2; hKCC2; Neuronal K-Cl cotransporter; SLC12A5; KCC2; KIAA1176]
Gene, Accession #[KCC2/SLC12A5], Gene ID: 57468, NCBI: Q9H2X9.3, UniProt: Q9H2X9
Catalog #MBS1752513
Price$315
Order / More InfoKCC2/SLC12A5 Antibody from MYBIOSOURCE INC.
Product Specific References1. Sallinen, R., Tornberg, J., Putkiranta, M., Horelli-Kuitunen, N., Airaksinen, M. S., Wessman, M. Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K( )-Cl(-) cotransporter (KCC2) defines a new region of conserved homology. Cytogenet. Cell Genet. 94: 67-70, 2001. Note: Erratum: Cytogenet. Genome Res. 98: 232 only, 2002. 2. Stodberg, T., McTague, A., Ruiz, A. J., Hirata, H., Zhen, J., Long, P., Farabella, I., Meyer, E., Kawahara, A., Vassallo, G., Stivaros, S. M., Bjursell, M. K. Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures. Nature Commun. 6: 8038, 2015. Note: Electronic Article.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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