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Antigenic Specificity | KCC2/SLC12A5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for KCC2/SLC12A5 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Potassium-chloride transporter member 5 is also known by the names: KCC2 (potassium chloride cotransporter 2) for its ionic substrates, and SLC12A5 for its genetic origin from the SLC12A5 gene in humans. It is mapped to 20q13.12. K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients |
Immunogen | Immunogen: E Coli-derived human KCC2/SLC12A5 recombinant protein (Position: A228-N833). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P). |
Other Names | [Solute carrier family 12 member 5; Solute carrier family 12 member 5; Electroneutral potassium-chloride cotransporter 2; K-Cl cotransporter 2; hKCC2; Neuronal K-Cl cotransporter; SLC12A5; KCC2; KIAA1176] |
Gene, Accession # | [KCC2/SLC12A5], Gene ID: 57468, NCBI: Q9H2X9.3, UniProt: Q9H2X9 |
Catalog # | MBS1752513 |
Price | $315 |
Order / More Info | KCC2/SLC12A5 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sallinen, R., Tornberg, J., Putkiranta, M., Horelli-Kuitunen, N., Airaksinen, M. S., Wessman, M. Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K( )-Cl(-) cotransporter (KCC2) defines a new region of conserved homology. Cytogenet. Cell Genet. 94: 67-70, 2001. Note: Erratum: Cytogenet. Genome Res. 98: 232 only, 2002. 2. Stodberg, T., McTague, A., Ruiz, A. J., Hirata, H., Zhen, J., Long, P., Farabella, I., Meyer, E., Kawahara, A., Vassallo, G., Stivaros, S. M., Bjursell, M. K. Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures. Nature Commun. 6: 8038, 2015. Note: Electronic Article. |