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Antigenic Specificity | SHP-2 |
Clone | [6G2-H4-F11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well a |
Immunogen | Immunogen: Purified recombinant fragment of human PTPN11 (AA: 263-329) expressed in E. Coli. |
Other Names | [PTPN11] |
Gene, Accession # | [SHP-2], Gene ID: 5781, NCBI: NP_002825.3, UniProt: Q06124 |
Catalog # | MBS8538956 |
Price | $280 |
Order / More Info | SHP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |