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Antigenic Specificity | MSLN (Mesothelin, CAK1 Antigen, MPF, Pre-pro-megakaryocyte-potentiating Factor, SMR) |
Clone | [10K75] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | ~0.5mg/ml (after reconstitution) |
Applications | ELISA (EL/EIA), Western Blot (WB), Simple Western (SW) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human Mesothelin. Does not recognize recombinant MPF. Megakaryocyte Potentiating Factor (MPF) is a 33kD soluble protein that is cleaved as an N-terminal propeptide from the mouse mesothelin preproprotein by furin, while the C-terminal portion is processed further to form mesothelin. Mouse MPF potentiates megakaryocyte colony forming activity of IL-3 in mouse bone marrow culture. Human MPF shows 55% aa identity with mouse or rat MPF. The preproprotein is produced by mesothelial cells and is also highly expressed in pancreatic, gastric and ovarian carcinomas. |
Immunogen | Immunogen: Purified, recombinant protein corresponding to aa296-580 from, human Mesothelin, expressed in NSO cells. Acession #: Q13421 |
Other Names | [-MSLN (Mesothelin, CAK1 Antigen, MPF, Pre-pro-megakaryocyte-potentiating Factor, SMR)], [MSLN; MSLN; MPF; SMRP; MPF; MPF] |
Gene, Accession # | Gene ID: 10232, NCBI: NP_001170826.1, UniProt: Q13421 |
Catalog # | MBS633277 |
Price | $680 |
Order / More Info | MSLN (Mesothelin, CAK1 Antigen, MPF, Pre-pro-megakaryocyte-potentiating Factor, SMR) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |