Edit |   |
---|---|
Antigenic Specificity | PMS2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is an protein A purified antibody directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2. BLAST analysis indicates that this sequence is 100% identical for human, mouse, rat and chimpanzee. No specific information is available for reactivity with PMS2 protein from other sources. PMS2 is a highly conserved nuclear protein involved in mismatch repair during DNA replication and has been identified to be composed as a heterodimer of PMS2 and MLH1. PMS is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. This associati |
Immunogen | Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with recombinant human PMS2 corresponding to the first 133 amino acid residues of the protein. The clone was produced using conventional hybridoma technology. |
Other Names | [Pms2; Pms2] |
Gene, Accession # | [PMS2], Gene ID: 36705 |
Catalog # | MBS4157791 |
Price | $540 |
Order / More Info | PMS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |