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Antigenic Specificity | 5-HT-3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: 5-HT-3A antibody detects endogenous levels of total 5-HT-3A. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.Subunit Structure: Forms pentahomomeric complex as well as pentaheteromeric complex with HTR3B or HTR3C or HTR3D or HTR3E; homomeric complex is functional but exhibits low conductance with modified voltage dependence, and decreased agonist and antagonist affinity. Interacts with RIC3.Similarity: Belo |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Junction, Synapse, Postsynaptic Cell Membrane. Cell Membrane. Tissue Specificity: Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. |
Other Names | [5 HT 3; 5 HT3 receptor; 5 HT3A; 5 HT3A receptor; 5 HT3RA; 5 hydroxytryptamine (serotonin) receptor 3A; 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT receptor; 5HT3 serotonin receptor; 5HT3A_HUMAN; 5HT3R; HTR3; Htr3a; Serotonin receptor 3A; Serotonin-gated ion channel receptor 3a; Serotonin-gated ion channel receptor] |
Gene, Accession # | [5-HT-3A], Gene ID: 3359, NCBI: NP_000860.2, UniProt: P46098 |
Catalog # | MBS9604959 |
Price | $240, $280 |
Order / More Info | 5-HT-3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |