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Antigenic Specificity | CDC2L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CDC2L1 antibody detects endogenous levels of total CDC2L1. Function: Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.Subunit Structure: Cleaved isoform SV9 (p110C) binds to the serine/threonine kinase PAK1 and RANBP9. p110C interacts with RNPS1. Isoform 7, but not isoform SV9, nor its cleavage product p110C, interacts with CCND3. Interacts with CCNL1 and CCNL2. Forms complexes with pre-mRNA-splicing factors, including at least SRSF1, SRSF2 AND SRSF7/SLU7. Interacts with isoform 5 of MYO18A (PubMed:25965346).Post-translational Modifications: During FAS- |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. Predicted Cross Reactivity: Pig, Bovine, Xenopus Similarity: Pig (100%), Bovine (100%), Xenopus (82%) |
Other Names | [CDC2L1; CDK11; Cell division cycle 2-like protein kinase 1; Cell division protein kinase 11B; CLK 1; EC=2.7.11.22; Galactosyltransferase associated protein kinase p58/GTA; ITSLRE serine/threonine protein kinase CDC2L1; p58 CLK 1; PITSLREA; PK58] |
Gene, Accession # | [CDC2L1], Gene ID: 984, NCBI: NP_001278274.1, UniProt: P21127 |
Catalog # | MBS9604581 |
Price | $240, $280 |
Order / More Info | CDC2L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |